BDBM50442875 NORSTICTIC ACID

SMILES Cc1cc(O)c(C=O)c2Oc3c4C(O)OC(=O)c4c(O)c(C)c3OC(=O)c12

InChI Key InChIKey=IEVVSJFLBYOUCJ-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50442875   

LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataKi:  420nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataIC50: 550nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataKi:  630nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataIC50: 1.15E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMediator of RNA polymerase II transcription subunit 25(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Med25 transcriptional activation in human MCF-7 cells by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
University of Utah College of Pharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442875BDBM50442875(NORSTICTIC ACID)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) assessed as inhibition constant measured up to 100 uM incubated up to 30 mins using DiFMUP as fluorogenic substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed