Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = '14 kDa phosphohistidine phosphatase'
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50442875(NORSTICTIC ACID)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) assessed as inhibition constant measured up to 100 uM incubated up to 30 mins using DiFMUP as fluorogenic substr...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50186231((2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)ac...)
Affinity DataKi:  1.83E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50220832(CHEMBL8211 | N-ethylmaleimide)
Affinity DataKi:  2.09E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50442875(NORSTICTIC ACID)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50186231((2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)ac...)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate incubated for 1 hr by multimode microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50056922(1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50239376(CHEBI:35817 | ROXARSONE)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target14 kDa phosphohistidine phosphatase(Homo sapiens)
University Of Utah College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240028(Acetarsol | Acetarsone | Gynoplix | S.V.C. | Stova...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of PHPT1 (unknown origin) using DiFMUP as fluorogenic substrate incubated for 30 mins followed by substrate addition and measured every 60...More data for this Ligand-Target Pair
In DepthDetails PubMed