BDBM81428 N-(naphthalen-2-yl)-2-[2-(pyridin-2-yl)-1H-1,3-benzodiazol-1-yl]acetamide, Compound C91
SMILES O=C(Cn1c(nc2ccccc12)-c1ccccn1)Nc1ccc2ccccc2c1
InChI Key InChIKey=XYCMWFINXXFAFG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 81428
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Streptococcus pyogenes (Firmicutes))
Brandeis University
Brandeis University
Affinity DataIC50: 5.40nMpH: 8.0 T: 25°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 8nMpH: 8.0 T: 25°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluoresce...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as NADH production preincubated for 5 mins by fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 8.0 T: 25°CAssay Description:Inhibition assay using inosine 5'-onophosphate dehydrogenase (IMPD).More data for this Ligand-Target Pair