BDBM50539899 CHEMBL4640028
SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(nc2c(nccc12)-c1ccn[nH]1)N1CCOCC1
InChI Key InChIKey=FAZDIAPBCWLARY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50539899
Affinity DataIC50: 59nMAssay Description:Inhibition of 5'-TAMRA-labeled tracer 3',6'-bis(dimethylamino)-N-(4-{[2(1H-indol-4-yl)-6-(morpholin-4-yl)-pyrimidin-4-yl]amino}butyl)-3-oxo-3H-spiro[...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bayer
Curated by ChEMBL
Bayer
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of recombinant human ERG stably expressed in HEK293 cells at -80 mV by whole cell voltage clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of ATR in human HT-29 cells assessed as reduction in histone H2AX phosphorylation measured after 30 mins by immunofluorescence cytometric ...More data for this Ligand-Target Pair