BDBM50508749 CHEMBL4546591

SMILES CC(=O)Nc1ncc(CN2CCC3(CCN(C3)c3cc(C)nc(C)c3)C2)s1

InChI Key InChIKey=IXQVLWJKRQGPGL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508749   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50508749(CHEMBL4546591)
Affinity DataIC50:  141nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed