BDBM50508749 CHEMBL4546591
SMILES CC(=O)Nc1ncc(CN2CCC3(CCN(C3)c3cc(C)nc(C)c3)C2)s1
InChI Key InChIKey=IXQVLWJKRQGPGL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50508749
Affinity DataIC50: 141nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
Affinity DataIC50: 141nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair