BDBM18512 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine::CHEMBL36::Pyrimethamine (Pyr)::US11530198, Example Pyrimethamine::cid_4993
SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
InChI Key InChIKey=WKSAUQYGYAYLPV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 18512
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair