BDBM50427622 CHEMBL2323508::US9346803, Table 2, Compound 10: 3-[1-(4-chlorobenzoyl)-3-ethyl-5-methoxy-1H-indol-2-yl]propanoic acid
SMILES CCc1c(CCC(O)=O)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12
InChI Key InChIKey=JBMSOEFHPCTJTH-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50427622
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant AKR1C3-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human recombinant AKR1C4-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of human recombinant AKR1C1-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of human recombinant AKR1C2-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of wild type mouse COX2 by discontinuous radioactive TLC assayMore data for this Ligand-Target Pair