BDBM50045776 CHEMBL982::JF-1::NALMEFENE::Nalmetrene::ORF-11676::Revex::cid_5284594

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=C)CC[C@@]35O

InChI Key InChIKey=WJBLNOPPDWQMCH-MBPVOVBZSA-N

Data  12 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50045776   

TargetKappa-type opioid receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50045776(CHEMBL982 | JF-1 | NALMEFENE | Nalmetrene | ORF-11...)
Affinity DataKi:  0.0830nMAssay Description:Displacement of [3H]U69,593 from human kappa-opioid receptor expressed in CHO cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50045776(CHEMBL982 | JF-1 | NALMEFENE | Nalmetrene | ORF-11...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DAMGO from human mu-opioid receptor expressed in CHO cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50045776(CHEMBL982 | JF-1 | NALMEFENE | Nalmetrene | ORF-11...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]naltrindole from human delta-opioid receptor expressed in CHO cell membranes after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed