BDBM194794 US9206167, 15::USRE48059, Compound of Example 15

SMILES O=C1CCc2ccc(OC\C=C\CN3CCN(CC3)c3cccc4sccc34)cc2N1

InChI Key InChIKey=PFDUTSYNBVBRFL-OWOJBTEDSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 194794   

TargetD(2) dopamine receptor(Rat)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM194794(US9206167, 15 | USRE48059, Compound of Example 15)
Affinity DataKi:  0.200nM ΔG°:  -13.2kcal/molepH: 7.4 T: 25°CAssay Description:The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Rat)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM194794(US9206167, 15 | USRE48059, Compound of Example 15)
Affinity DataKi:  3.30nM ΔG°:  -12.0kcal/molepH: 7.4 T: 37°CAssay Description:The assay was performed according to the method by Leysen J E et al. (Leysen J E, Niemegeers C J E, Van Nueten J M and Laduron P M. [3H] Ketanserin (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent