BDBM207624 US10501467, Example 69::US9260440, 69::US9617273, Example 69
SMILES C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
InChI Key InChIKey=HNHYFXQIDONXEC-MRXNPFEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 207624
Affinity DataIC50: 0.900nMpH: 8.0Assay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
TargetIsoform 2 of Protein mono-ADP-ribosyltransferase PARP3 (Long)(Homo sapiens (Human))
Beigene
US Patent
Beigene
US Patent
Affinity DataIC50: 185nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Affinity DataIC50: 766nMAssay Description:Tankyrase-2 enzymatic assay was conducted using commercial Tankyrase-2 Chemiluminescent Assay Kit (BPS Biosciences) and the protocol with the kit. GS...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair