BDBM11611 β-CA inhibitor, 10::4-Amino-3,5-dibromobenzenesulfonamide::4-amino-3,5-dibromobenzene-1-sulfonamide::CHEMBL306195::halogenosulfanilamide deriv. 12

SMILES Nc1c(Br)cc(cc1Br)S(N)(=O)=O

InChI Key InChIKey=DLXJPWSYRLLYSV-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11611   

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  410nM ΔG°:  -8.71kcal/molepH: 8.3 T: 25°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  2.03E+3nM ΔG°:  -7.76kcal/molepH: 8.3 T: 25°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  4.52E+3nM ΔG°:  -7.29kcal/molepH: 8.3 T: 25°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed