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Found 5 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM11611'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  73nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  73nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  73nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  73nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11611(β-CA inhibitor, 10 | 4-Amino-3,5-dibromobenze...)
Affinity DataKi:  4.52E+3nM ΔG°:  -30.5kJ/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed