BDBM439497 US10633379, Example 35::US10633379, Example 82
SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1Oc1c(C)cc(F)cc1C)C(C)(C)O
InChI Key InChIKey=OEDSFMUSNZDJFD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 439497
Affinity DataKi: 1nMAssay Description:Inhibition of BRDT BD2 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of human N-terminal His6 tagged BRD4 BD2 (352 to 457) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of N-terminal His6-tagged human BRD2 BD2 (348 to 455 residues) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 426nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Affinity DataKi: 520nMAssay Description:Inhibition of human N-terminal His6 tagged BRD4 BD1 (57 to 168) residues expressed in Escherichia coli BL21(DE3) cells after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 917nMAssay Description:Inhibition of BRDT BD1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+3nMAssay Description:Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution. Compound dilutions were added directly into white, low-vo...More data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Inhibition of N-terminal His6-tagged human BRD2 BD1 (73 to 194 residues) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.14E+3nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of NanoLuc-tagged BRD4 BD2 (unknown origin) expressed in human HeLa cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of NanoLuc-tagged BRD4 BD1 (unknown origin) expressed in human HeLa cells after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair