BDBM50357333 CHEMBL1916891

SMILES CN(C)C\C=C\C(=O)N(C)c1cc2c(cc1F)nc(Nc1ccccc1C)c1cncn21

InChI Key InChIKey=YMSXHRWUGLAAKL-JXMROGBWSA-N

Data  23 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50357333   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of EGFR preincubated for 60 mins measured after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50:  17.2nMAssay Description:Inhibition of EGFR after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50:  75.6nMAssay Description:Inhibition of EGFR relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed