BDBM50357333 CHEMBL1916891
SMILES CN(C)C\C=C\C(=O)N(C)c1cc2c(cc1F)nc(Nc1ccccc1C)c1cncn21
InChI Key InChIKey=YMSXHRWUGLAAKL-JXMROGBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50357333
Affinity DataIC50: 1.93nMAssay Description:Inhibition of human full-length BTK expressed in Sf9 cells using FAM-Srctide peptide as substrate after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
Affinity DataIC50: 772nMAssay Description:Inhibition of C-terminal His6-tagged human full-length LCK expressed in Sf9 cells after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 298nMAssay Description:Inhibition cSRC expressed in Sf9 cells after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human full-length BTK expressed in Sf9 cells using FAM-Srctide peptide as substrate preincubated for 60 mins measured after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 353nMAssay Description:Inhibition of LYN-A expressed in Sf9 cells preincubated for 60 mins measured after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 755nMAssay Description:Inhibition of C-terminal His6-tagged human full-length LCK expressed in Sf9 cells preincubated for 60 mins measured after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition cSRC expressed in Sf9 cells preincubated for 60 mins measured after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of EGFR preincubated for 60 mins measured after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 17.2nMAssay Description:Inhibition of EGFR after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of BTK autophosphorylation at PY223 in human Ramos B cells after 20 mins by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 892nMAssay Description:Inhibition of FYN relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 75.6nMAssay Description:Inhibition of EGFR relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 43.7nMAssay Description:Inhibition of ERBB4 relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of EPHB3 relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of Abl1 relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of BLK relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 1.53nMAssay Description:Inhibition of BMX relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 3.31nMAssay Description:Inhibition of BTK relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 434nMAssay Description:Inhibition of EPHA8 relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 611nMAssay Description:Inhibition of FRK relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 1.93nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 624nMAssay Description:Inhibition of LYN-A expressed in Sf9 cells after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair