BDBM580669 US11492346, Example 9::US11492346, Example 90::US11492346, Example 91::US11492346, Example 98

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

InChI Key InChIKey=VNSQFPFWUAZOTQ-UHFFFAOYSA-N

Data  27 KI

PDB links: 1 PDB ID matches this monomer.

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Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 580669   

TargetHistone acetyltransferase KAT8(Human)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  500nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone acetyltransferase KAT8(Human)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  660nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone acetyltransferase KAT8(Human)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  730nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetHistone acetyltransferase KAT8(Human)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  820nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent