BDBM580669 US11492346, Example 9::US11492346, Example 90::US11492346, Example 91::US11492346, Example 98

SMILES COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

InChI Key InChIKey=VNSQFPFWUAZOTQ-UHFFFAOYSA-N

Data  27 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 580669   

TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.350nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.380nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.420nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.460nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.660nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.740nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.75nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.800nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.830nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  1.23nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  1.30nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  1.38nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  1.55nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  1.63nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6B(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  2.82nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  40nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  50nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  60nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  60nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  370nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  500nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  570nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  610nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  620nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  660nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  730nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone acetyltransferase KAT8(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  820nMAssay Description:TBDA. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM com...More data for this Ligand-Target Pair
In DepthDetails US Patent