BDBM50335242 3-Chloro-3'-((2-cyclopentyl-3-oxo-2,3-dihydrobenzo[d]isothiazol-6-yloxy)methyl)biphenyl-4-carboxylic Acid::CHEMBL1651219
SMILES OC(=O)c1cc(ccc1Cl)-c1cccc(COc2ccc3c(c2)sn(C2CCCC2)c3=O)c1
InChI Key InChIKey=ZQBPXBADOJMCRU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50335242
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK-293 cells assessed as thaillium flux through GIRK channelsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Sanford-Burnham Medical Research Institute
Curated by ChEMBL
Affinity DataEC50: 170nMAssay Description:Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair