BDBM50357333 CHEMBL1916891
SMILES CN(C)C\C=C\C(=O)N(C)c1cc2c(cc1F)nc(Nc1ccccc1C)c1cncn21
InChI Key InChIKey=YMSXHRWUGLAAKL-JXMROGBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50357333
Affinity DataIC50: 1.93nMAssay Description:Inhibition of human full-length BTK expressed in Sf9 cells using FAM-Srctide peptide as substrate after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human full-length BTK expressed in Sf9 cells using FAM-Srctide peptide as substrate preincubated for 60 mins measured after 60 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of BTK autophosphorylation at PY223 in human Ramos B cells after 20 mins by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.31nMAssay Description:Inhibition of BTK relative to controlMore data for this Ligand-Target Pair
Affinity DataIC50: 1.93nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair