BDBM50607924 CHEMBL5278864

SMILES NC(=O)C(=C/c1cccc(c1)-c1ncnc2[nH]ccc12)\C#N

InChI Key InChIKey=PBACTZXZNFJQGT-GHXNOFRVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50607924   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50607924(CHEMBL5278864)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50607924(CHEMBL5278864)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of JAK3 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50607924(CHEMBL5278864)
Affinity DataIC50:  56nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 45 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed