BDBM50357333 CHEMBL1916891

SMILES CN(C)C\C=C\C(=O)N(C)c1cc2c(cc1F)nc(Nc1ccccc1C)c1cncn21

InChI Key InChIKey=YMSXHRWUGLAAKL-JXMROGBWSA-N

Data  23 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357333   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50:  772nMAssay Description:Inhibition of C-terminal His6-tagged human full-length LCK expressed in Sf9 cells after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataIC50:  755nMAssay Description:Inhibition of C-terminal His6-tagged human full-length LCK expressed in Sf9 cells preincubated for 60 mins measured after 60 mins by TR-FRET AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed