BDBM85097 CAS_181632-25-7::CHEMBL14563::SB 242084
SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Cl
InChI Key InChIKey=GIUZEIJUFOPTMR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 85097
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 2C19Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 2D6Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 2C9Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 1A2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 1A2 at 500 uMMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 3A4Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 2D6 at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 2C9 at 100 uMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataIC50: 0.330nMAssay Description:Antagonist activity at recombinant human 5-HT2C expressed in human U2OS cells by pathhunter beta-arrestin assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 19A1 at 100 uMMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 3A at 1 uMMore data for this Ligand-Target Pair