BDBM11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride
SMILES CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O
InChI Key InChIKey=BGRJTUBHPOOWDU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 190 hits for monomerid = 11638
Affinity DataKi: 0.800nM ΔG°: -12.2kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of full length human recombinant CA VIMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 12 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Ki value against human carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Compound was tested for its ability to displace [3H]- spiperone from Dopamine receptor D2 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Binding affinity to D2R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(African malaria mosquito)
University of Tampere and Tampere University Hospital
Curated by ChEMBL
University of Tampere and Tampere University Hospital
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of Anopheles gambiae carbonic anhydrase pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 31nM ΔG°: -10.1kcal/molepH: 7.5 T: 22°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -9.98kcal/molepH: 7.5 T: 22°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 40nM ΔG°: -9.92kcal/molepH: 7.5 T: 20°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human carbonic anhydrase 2 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant carbonic anhydrase-2 by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Inhibition of recombinant human carbonic anhydrase-2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair