BDBM50012477 1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester::1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester(Carefentanil)::CARFENTANIL::CHEMBL290429::Carfentanil1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester::US20230399418, Compound Carfentanil

SMILES CCC(=O)N(c1ccccc1)C1(CCN(CCc2ccccc2)CC1)C(=O)OC

InChI Key InChIKey=YDSDEBIZUNNPOB-UHFFFAOYSA-N

Data  10 KI  2 IC50  1 Kd  1 EC50  1 Koff  1 Kon

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50012477   

TargetMu-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  0.0240nMAssay Description:Binding affinity against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  0.0240nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  0.0900nMAssay Description:Inhibition of [3H]DAGO binding to rat brain membrane Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of [3H]diprenorphine binding to rat brain membrane opioid receptors;(T= total opioid receptor family)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity against Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  9nMAssay Description:Opioid receptor kappa 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  43nMAssay Description:Binding affinity against Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50012477(1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-...)
Affinity DataKi:  92nMAssay Description:Opioid receptor kappa 1 apparent binding constant from guinea pig cerebellum using [3H]diprenorphine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed