BDBM7882 1H-imidazole::CHEMBL540::Imidazole (Im)::US9138393, Imidazole::US9144538, Imidazole::imidazole

SMILES c1c[nH]cn1

InChI Key InChIKey=RAXXELZNTBOGNW-UHFFFAOYSA-N

Data  6 KI  7 IC50  2 Kd

PDB links: 123 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 7882   

LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi:  229nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(Rat)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi:  1.00E+5nM ΔG°:  -5.54kcal/molepH: 8.0 T: 30°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi:  1.60E+5nM ΔG°:  -5.26kcal/molepH: 8.0 T: 30°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM7882(1H-imidazole | CHEMBL540 | Imidazole (Im) | US9138...)
Affinity DataKi:  1.75E+5nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed