BDBM129823 US8815926, 102
SMILES COc1ncc(-c2nc3C(=O)N([C@H](c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)cn(C)c2=O)c(OC)n1
InChI Key InChIKey=AGBSXNCBIWWLHD-FQEVSTJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 129823
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine
Curated by ChEMBL
International Institute For Translational Chinese Medicine
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine
Curated by ChEMBL
International Institute For Translational Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human MDM2 by TR-FRET assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine
Curated by ChEMBL
International Institute For Translational Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair