BDBM110029 US20240252496, Example ACY-257::US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [82]

SMILES COC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=ORGWELKYNBOLPD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 110029   

TargetHistone deacetylase 6(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 12nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 12nMAssay Description:The mouse-center-based representative traces of vehicle-treated mice showed more activity in the food zone when compared to the ACY775-treated mice a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 13nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
The Children'S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 268nMAssay Description:The mouse-center-based representative traces of vehicle-treated mice showed more activity in the food zone when compared to the ACY775-treated mice a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
The Children'S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 268nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
The Children'S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 530nMAssay Description:The mouse-center-based representative traces of vehicle-treated mice showed more activity in the food zone when compared to the ACY775-treated mice a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
The Children'S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 530nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 850nMAssay Description:The CPP assay was performed 6 h later under the ad libitum feeding condition (n=10 mice for both the Vehicle- and ACY775-treated groups). CPP assay u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 850nMAssay Description:The mouse-center-based representative traces of vehicle-treated mice showed more activity in the food zone when compared to the ACY775-treated mice a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
The Children’S Medical Center

US Patent
LigandPNGBDBM110029(US8609678, 4-(bis(4-fluorophenyl)(methoxy)methyl)-...)
Affinity DataIC50: 1.23E+3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent