BDBM14490 6-{2-[4-(dimethylamino)phenyl]ethynyl}-2-methyl-5-phenylpyrimidin-4-amine::CHEMBL276470::alkynylpyrimidine 4

SMILES CN(C)c1ccc(cc1)C#Cc1nc(C)nc(N)c1-c1ccccc1

InChI Key InChIKey=VCOLEQQWAHFJIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14490   

TargetAdenosine kinase(Rat)
Abbott Laboratories

LigandPNGBDBM14490(CHEMBL276470 | 6-{2-[4-(dimethylamino)phenyl]ethyn...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2007
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM14490(CHEMBL276470 | 6-{2-[4-(dimethylamino)phenyl]ethyn...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cytosolic adenosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed