BDBM158170 US9029360, 13

SMILES Cc1nc2CCN(CCc2s1)C(=O)c1cc2ncc(Cl)cn2n1

InChI Key InChIKey=WOOXFLPCMNOANB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158170   

TargetMetabotropic glutamate receptor 5(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158170(US9029360, 13)
Affinity DataIC50: 63nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158170(US9029360, 13)
Affinity DataIC50: 1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent