BDBM191037 US10077266, Example 149::US10406157, Compound A::US9181249, 149::US9708313, 149

SMILES CC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(N[C@H]3CCOC3)nc2C1

InChI Key InChIKey=HSWVJQBEXRKOBZ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191037   

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 191037BDBM191037(US9708313, 149 | US9181249, 149 | US10077266, Exam...)
Affinity DataKi:  6nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetG-protein coupled receptor 6(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 191037BDBM191037(US9708313, 149 | US9181249, 149 | US10077266, Exam...)
Affinity DataIC50: 505nMAssay Description:The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent