BDBM192165 US9187441, 8l

SMILES CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1ccc(Cl)cc1

InChI Key InChIKey=OTUBDDRFPQLPKD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 192165   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Pittsburgh

US Patent
LigandChemical structure of BindingDB Monomer ID 192165BDBM192165(US9187441, 8l)
Affinity DataKi:  1.80E+3nM ΔG°:  -7.70kcal/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Pittsburgh

US Patent
LigandChemical structure of BindingDB Monomer ID 192165BDBM192165(US9187441, 8l)
Affinity DataKi:  2.00E+3nM ΔG°:  -7.64kcal/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Pittsburgh

US Patent
LigandChemical structure of BindingDB Monomer ID 192165BDBM192165(US9187441, 8l)
Affinity DataKi:  5.00E+3nM ΔG°:  -7.11kcal/moleT: 2°CAssay Description:Fluorescent polarization experiments were performed as follows. Briefly, the fluorescence polarization experiments were read on an Ultra Evolution 38...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2016
Entry Details
US Patent