BDBM206030 US9255103, 31

SMILES C[C@@H]%10Cc1c([nH]c2ccccc12)[C@@H](c9cnc(N8CCC(CN3CCC7(CC3)COc6cc5C(=O)N(C4CCC(=O)NC4=O)Cc5cc67)CC8)nc9)N%10CC(F)(F)CO

InChI Key InChIKey=DRTKCRBMELMEQA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 206030   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206030BDBM206030(3-(1'-((1-(5-((1R,3R)-2-(2,2-difluoro-3- hydroxypr...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 206030BDBM206030(3-(1'-((1-(5-((1R,3R)-2-(2,2-difluoro-3- hydroxypr...)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent