BDBM256545 US10435361, Example 44::US9481648, 44::US9790174, Example 44

SMILES COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(C(=O)NCC(O)=O)c4OC)C(C)(C)C)c4ccccc34)n2)cc(OC)c1

InChI Key InChIKey=QNHHGBAOFUVYRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 256545   

TargetGlycogen synthase kinase-3 alpha(Human)
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US Patent
LigandPNGBDBM256545(US9481648, 44 | US9790174, Example 44 | US10435361...)
Affinity DataIC50: 80nMAssay Description:Method 2: This method follows the same steps as Method 1 above, but utilises a shorter period of mixing of the test compound (105 minutes instead of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
Respivert

US Patent
LigandPNGBDBM256545(US9481648, 44 | US9790174, Example 44 | US10435361...)
Affinity DataIC50: 80nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent