BDBM25979 BMCL18324 Compound 1::N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide::biphenyl amide, 2
SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2cc(ccc2C)-c2nnc(C)o2)cc1N1CCN(C)CC1
InChI Key InChIKey=KPNDZYJBDZIKBN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 25979
Affinity DataKi: 1.60E+3nM ΔG°: -7.82kcal/mole IC50: 1.00E+4nMpH: 7.5 T: 22°CAssay Description:Fluorescence polarization assays used GST-tagged enzyme and an ATP-competitive Rhodamine-green labelled fluoroligand. These components were dissolved...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nM ΔG°: -7.82kcal/mole IC50: 1.00E+4nMpH: 7.5 T: 22°CAssay Description:Fluorescence polarization assays used GST-tagged enzyme and an ATP-competitive Rhodamine-green labelled fluoroligand. These components were dissolved...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nM ΔG°: -7.49kcal/mole IC50: 8.40E+3nMpH: 7.4 T: 22°CAssay Description:Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nM ΔG°: >-7.28kcal/mole IC50: >1.60E+4nMpH: 7.5 T: 22°CAssay Description:Fluorescence polarization assays used GST-tagged enzyme and an ATP-competitive Rhodamine-green labelled fluoroligand. These components were dissolved...More data for this Ligand-Target Pair