BDBM259804 US9505766, Me acrylate (2)
SMILES COC(=O)\C=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO
InChI Key InChIKey=SUWNTOBZXIAHKB-CMDGGOBGSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 259804
TargetRibosomal protein S6 kinase alpha-3 [399-740](Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 250nMpH: 8.0 T: 22°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of RSK2 in human MDA-MB-231 cells after 2 hrsMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3 [399-740,C436V](Human)
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 190nMpH: 8.0 T: 22°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair