BDBM259804 US9505766, Me acrylate (2)

SMILES COC(=O)\C=C\c1c(-c2ccc(C)cc2)c2c(N)ncnc2n1CCCO

InChI Key InChIKey=SUWNTOBZXIAHKB-CMDGGOBGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 259804   

TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259804(US9505766, Me acrylate (2))
Affinity DataIC50:  250nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM259804(US9505766, Me acrylate (2))
Affinity DataIC50:  250nMAssay Description:Inhibition of RSK2 in human MDA-MB-231 cells after 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3 [399-740,C436V](Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM259804(US9505766, Me acrylate (2))
Affinity DataIC50:  190nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent