BDBM276170 2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 77::US10233173, Example 77

SMILES Cc1cnc(OCc2cn(nn2)-c2ccc(F)c(c2)C(C)(F)F)nc1

InChI Key InChIKey=UVNKBHYJPIJAII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276170   

TargetRetinoic acid receptor RXR-alpha(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276170(2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triaz...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276170(2-[[1-[3-(1,1-Difluoroethyl)-4-fluoro-phenyl]triaz...)
Affinity DataIC50: 4nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent