BDBM278583 (2E)-3-(3-Fluoro-1-{[5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)-1,2-oxazol-4-yl]carbonyl}-1H-indol-4-yl)prop-2-enoic acid ::US10040791, Example 45
SMILES CC(C)(F)c1onc(c1C(=O)n1cc(F)c2c(\C=C\C(O)=O)cccc12)-c1c(Cl)cc(Cl)cc1Cl
InChI Key InChIKey=ZWPYXTYCFJBBGS-VOTSOKGWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 278583
Affinity DataIC50: 114nMpH: 7.5 T: 25°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.5 T: 25°CAssay Description:The IDH1R132H protein and the IDH1R132C protein were prepared as follows: the IDH1R132H or IDH1R132C gene was integrated into a pET24b(+) vector (Nov...More data for this Ligand-Target Pair