BDBM307690 US10150755, Compound 82

SMILES C[C@@H]1CCc2nnc(-c3cccc(n3)N3Cc4ccccc4C3=O)n12

InChI Key InChIKey=JHXGRCVWBSONFR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307690   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Seal Rock Therapeutics

US Patent
LigandPNGBDBM307690(US10150755, Compound 82)
Affinity DataKi: <200nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Seal Rock Therapeutics

US Patent
LigandPNGBDBM307690(US10150755, Compound 82)
Affinity DataIC50: 200nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent