BDBM31217 2-phenoxybenzoyltryptophan derivative, R3C3

SMILES OC(=O)[C@H](Cc1cn(C(=O)OCc2ccccc2)c2cc(F)ccc12)NC(=O)c1ccccc1Oc1ccccc1

InChI Key InChIKey=JTDAJTALRFKEKO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31217   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandPNGBDBM31217(2-phenoxybenzoyltryptophan derivative, R3C3)
Affinity DataKi:  800nM ΔG°:  -8.26kcal/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed