BDBM31225 2-phenoxybenzoyltryptophan derivative, R5C3

SMILES Cc1ccc2n(cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(O)=O)c2c1)C(=O)OCc1ccccc1

InChI Key InChIKey=FHNQOOZTZWBWQO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31225   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Schering-Plough Research Institute

LigandPNGBDBM31225(2-phenoxybenzoyltryptophan derivative, R5C3)
Affinity DataKi:  100nM ΔG°:  -9.48kcal/molepH: 7.4 T: 2°CAssay Description:Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed