BDBM313756 US10167285, Example (2exp)

SMILES Cc1ncc2NC(Sc3c(Br)ccc(Cl)c3Cl)N(CCCC#C)c2n1

InChI Key InChIKey=WIDLBQYPALQEPG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313756   

TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313756(US10167285, Example (2exp))
Affinity DataEC50:  50.8nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313756(US10167285, Example (2exp))
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313756(US10167285, Example (2exp))
Affinity DataIC50: 365nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent