BDBM313756 US10167285, Example (2exp)

SMILES Cc1ncc2NC(Sc3c(Br)ccc(Cl)c3Cl)N(CCCC#C)c2n1

InChI Key InChIKey=WIDLBQYPALQEPG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313756   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313756(US10167285, Example (2exp))
Affinity DataEC50:  50.8nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313756(US10167285, Example (2exp))
Affinity DataIC50:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313756(US10167285, Example (2exp))
Affinity DataIC50:  365nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent