BDBM31473 substituted biphenyl derivative, 36m

SMILES CC(C)CNC(=O)c1ccc(c(c1)C(O)=O)-c1ccc(\C=C/CO)cc1C(=O)Nc1ccc(cc1)C(N)=N

InChI Key InChIKey=RMVFYPMRRGCHJM-ARJAWSKDSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31473   

TargetCoagulation factor VII(Human)
Biocryst Pharmaceuticals

LigandPNGBDBM31473(substituted biphenyl derivative, 36m)
Affinity DataIC50:  52nMpH: 7.2 T: 23°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Human)
Biocryst Pharmaceuticals

LigandPNGBDBM31473(substituted biphenyl derivative, 36m)
Affinity DataIC50:  6.62E+3nMT: 25°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Human)
Biocryst Pharmaceuticals

LigandPNGBDBM31473(substituted biphenyl derivative, 36m)
Affinity DataIC50:  2.27E+4nMT: 25°CAssay Description:Thrombin assay reactions were performed in a reaction mixture containing thrombin, and test compounds were added at varied concentrations. The reacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bovine)
Biocryst Pharmaceuticals

LigandPNGBDBM31473(substituted biphenyl derivative, 36m)
Affinity DataIC50:  1.77E+3nMT: 25°CAssay Description:Trypsin assay reactions were performed in a mixture containing trypsin, and test compounds were added at varied concentrations. The reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed