BDBM321260 N-[3-(benzylmethylamino)propyl]-4-butylbenzamide::US10179761, Compound 3.1.3

SMILES CCCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1

InChI Key InChIKey=QHTZTRVKDYEVCN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 321260   

TargetSigma non-opioid intracellular receptor 1(Human)
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321260(US10179761, Compound 3.1.3 | N-[3-(benzylmethylami...)
Affinity DataKi:  7.30nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321260(US10179761, Compound 3.1.3 | N-[3-(benzylmethylami...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H](+)-pentazocine from S1R in human Jurkat cell membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM321260(US10179761, Compound 3.1.3 | N-[3-(benzylmethylami...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM321260(US10179761, Compound 3.1.3 | N-[3-(benzylmethylami...)
Affinity DataKi:  49nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent