BDBM321260 N-[3-(benzylmethylamino)propyl]-4-butylbenzamide::US10179761, Compound 3.1.3

SMILES CCCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1

InChI Key InChIKey=QHTZTRVKDYEVCN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 321260   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321260(N-[3-(benzylmethylamino)propyl]-4-butylbenzamide |...)
Affinity DataKi:  7.30nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante

US Patent
LigandPNGBDBM321260(N-[3-(benzylmethylamino)propyl]-4-butylbenzamide |...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H](+)-pentazocine from S1R in human Jurkat cell membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321260(N-[3-(benzylmethylamino)propyl]-4-butylbenzamide |...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-DTG from S2R in human Jurkat cell membranes after 1 hr in presence of (+)-pentazocine by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM321260(N-[3-(benzylmethylamino)propyl]-4-butylbenzamide |...)
Affinity DataKi:  49nMAssay Description:The σ binding assays were performed according to Ganapathy et al. (Ganapathy, M. E.; Prasad, P. D.; Huang, W.; Seth, P.; Leibach, F. H.; Ganapat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent