BDBM349617 (3-(4-(2-(sec- butylamino)ethyl)phenoxy)-6- hydroxybenzo[b]thiophen-2-yl)(4-fluoro- 2,6-dimethylphenyl)methanone::US10208011, Compound 111::US10981887, Compound 111

SMILES CCC(C)NCCc1ccc(Oc2c(sc3cc(O)ccc23)C(=O)c2c(C)cc(F)cc2C)cc1

InChI Key InChIKey=NWNXQCBIXYHKEA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 349617   

TargetG-protein coupled estrogen receptor 1(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349617((3-(4-(2-(sec- butylamino)ethyl)phenoxy)-6- hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:A screening strategy was implemented utilizing an In-Cell Western assay to measure their ability to degrade the estrogen receptor in vitro. MCF7 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349617((3-(4-(2-(sec- butylamino)ethyl)phenoxy)-6- hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:All reagents used in this assay was supplied in the Human ERα Reporter Assay by Indigo Biosciences #IB00401. In an effort to screen selective es...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent

TargetEstrogen receptor(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349617((3-(4-(2-(sec- butylamino)ethyl)phenoxy)-6- hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:A screening strategy was implemented utilizing an In-Cell Western assay to measure their ability to degrade the estrogen receptor in vitro. MCF7 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent

TargetG-protein coupled estrogen receptor 1(Human)
G1 Therapeutics

US Patent
LigandPNGBDBM349617((3-(4-(2-(sec- butylamino)ethyl)phenoxy)-6- hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:All reagents used in this assay was supplied in the Human ERα Reporter Assay by Indigo Biosciences # IB00401. In an effort to screen selective e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
US Patent