BDBM358691 (S)-1-(5-(4-amino-5-chloropyrrolo [2,1-f][1,2,4]triazin-7-yl)-2- fluorophenyl)-3,3,6-trimethyl-4-(2- (methylsulfonyl)acetyl)piperazin-2-one::US10214537, Example 769
SMILES C[C@H]1CN(C(=O)CS(C)(=O)=O)C(C)(C)C(=O)N1c1cc(ccc1F)-c1cc(Cl)c2c(N)ncnn12
InChI Key InChIKey=VEYFBNORVXDVCH-LBPRGKRZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358691
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 0.200nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair