BDBM368925 4-(5-cyclopropyl-7H-pyrrolo[2,3-d]pyrimidin- 4-yl)-N-[(4-fluorophenyl)methyl]piperazine-1- carboxamide::US10227357, Compound P-0179

SMILES COc1cc(C2CC(=O)Nc3n[nH]cc32)ccc1OCc1ccc(C)cc1C(F)(F)F

InChI Key InChIKey=MPBULGNIWQLCEN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368925   

TargetSteroid hormone receptor ERR1 [181-423](Human)
Lead Pharma Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 368925BDBM368925(4-(3-methoxy-4-{[4-methyl-2-(trifluoromethyl)pheno...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent